(FAQ) DAXXIFY® vs. BOTOX®: Choosing Your Best Option

woman (model) with smooth skin looking off camera as she touches her cheek

At CaloSpa® Rejuvenation Center, we understand that achieving a youthful look is a personalized process. This blog post will compare DAXXIFY and BOTOX—2 key players in the realm of neuromodulators that help erase dynamic wrinkles with impressive results.

Whether you’re familiar with neuromodulators or just beginning to consider your options, understanding the differences and similarities between these treatments can help you decide what’s best for your skin.

1.    How Do DAXXIFY & BOTOX Work?

Dynamic wrinkles are those inevitable lines caused by repeated facial expressions, such as smiling or frowning. Treatments such as DAXXIFY and BOTOX temporarily relax the targeted facial muscles, smoothing out these wrinkles and preventing new ones from forming.

2.    How Do DAXXIFY & BOTOX Differ in Formulation and Longevity?

DAXXIFY and BOTOX target the same types of facial wrinkles but differ in their formulations and the duration of their effects.

  • Formulation: DAXXIFY uses Peptide Exchange Technology™ without human or animal-based components. BOTOX is a tried-and-true neuromodulator that uses a different formulation containing human serum albumin.
  • Longevity: DAXXIFY results can last from 6 up to 9 months, whereas BOTOX generally maintains its effects for about 3 to 4 months.

3.    Is DAXXIFY Better Than BOTOX?

This question often arises, but the answer depends on your needs and preferences. If longevity and fewer treatments throughout the year are priorities, DAXXIFY may be your better choice. However, if you’re new to neuromodulators, starting with BOTOX can give you a good baseline to understand how these treatments affect your facial aesthetics.

4.    How Much Do These Treatments Cost?

DAXXIFY may represent a higher initial investment than BOTOX. However, given its longer-lasting effects, it’s important to consider both the frequency of treatments and your budget when making your decision. Since each patient’s treatment is customized, prices will vary. At your consultation, we’ll provide a detailed estimate based on your needs and goals.

Learn why choosing a reputable, experienced provider for your injectable treatments is essential in this related blog post.

5.    Who Are the Best Candidates for DAXXIFY & BOTOX?

Both treatments are suitable for men and women who wish to reduce the appearance of dynamic wrinkles. Ideal candidates for DAXXIFY are often comfortable with neuromodulators and seeking a longer-lasting solution. Candidates for BOTOX may be new to neuromodulators or simply prefer the well-established effects and timeline of BOTOX.

6.    Are There Any Side Effects Associated With DAXXIFY & BOTOX?

Both treatments are generally well-tolerated. Common side effects include temporary bruising, swelling at the injection site, or a mild headache. These symptoms usually resolve quickly. During your consultation, we will review your health history to ensure you are a suitable candidate for these treatments.

7.    Can DAXXIFY & BOTOX Be Combined With Other Treatments?

Many of our patients combine neuromodulators with other treatments for enhanced results. For example, dermal fillers such as JUVÉDERM® restore volume, while neuromodulators smooth out wrinkles for comprehensive rejuvenation.

Take the Next Step

Choosing between DAXXIFY and BOTOX is a decision tailored to your personal goals and lifestyle needs. At CaloSpa® Rejuvenation Center, we help you navigate these options and select the treatment that best suits you. Call our office at (502) 814-3000 or to request a consultation.

Leave a Reply

Fields marked with * are required.


It's easy to stay connected to our plastic surgeons and providers and discover the experiences of our actual patients.


View Blog
  • Facebook
  • Reviews